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Conductive scaffolds for guided neural network formation Background: The present invention relates to the fabrication of patterned conductive scaffolds of micro and/or nanofibers with the help of printing techniques (e.g., near-field electrostatic printing, inkjet printing) and the formation of two-dimensional (2D) or three-dimensional (3D) neural networks guided by the conductive patterns under electrical... Published: 2/10/2021   |   Updated: 2/10/2021   |   Inventor(s):   Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Bougie With Improved Sensory Feedback Boug Illuminator ("Bougie Light") 1.8 million patients per year require emergency intubations to protect their airway and continue airflow into the lungs. In these emergency situations, it is crucial to intubate a patient’s trachea successfully on the first attempt. However with current tools, as many as 25% of all emergency intubations... Published: 2/10/2021   |   Updated: 2/10/2021   |   Inventor(s):   Keywords(s): Biotech, Medial Devices Category(s): Bio Technology (Rx, dev's, sys)

URETERAL STENT AND RETRIEVAL MEANS Background The current gold standard for a ureteral stent is a double-J stent made from a polymeric material. The stent is comprised of a curl at the proximal end of the stent, located in the kidney, and distal end of the stent, located in the bladder. A hydrophilic coating is typically added to the stent to decrease friction, resulting in a smoother... Published: 2/10/2021   |   Updated: 2/10/2021   |   Inventor(s): Michael Stifelman Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Artificial Cornea with Double-Side-Microtextured pHEMA Hydrogel Artificial Cornea with Double-Side Microtextured pHEMA Hydrogel Background As stated by World Health Organization (WHO), over 10 million people suffer from corneal blindness globally and 285 million people are visually impaired; however, only 1/50 of the patients obtained corneal transplants each year worldwide due to lack of donor tissue. In addition,... Published: 2/10/2021   |   Updated: 2/10/2021   |   Inventor(s):   Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Dual Modulus Scaffold Designs for Bone Graft Incorporation and Stability Background Bone is the second most transplanted tissue with approximately 2.2 million grafting procedures performed annually worldwide as a result of trauma, infection, or disease. Issues associated with the gold standard use of autografts and allografts, particularly when massive quantities are needed, have stimulated the development of synthetic... Published: 2/10/2021   |   Updated: 2/10/2021   |   Inventor(s): Rebecca Chung, Antonio Valdevit, Dilhan Kalyon Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Template-Free Assembly of Polymer Nanocapsules Hollow polymer capsules of controlled sizes for controlled delivery of organic molecules consist essentially of homopolymers. The capsules may be prepared by a facile, single-step self-assembly of an amphiphilic polyacid and a dispersing homopolymer. Assembled structures may be prepared to be reversibly dissolved via pH variations, or may be stabilized... Published: 2/10/2021   |   Updated: 7/30/2018   |   Inventor(s): Svetlana Sukhishvili, Yuhao Wang Keywords(s): Biotech, Diagnostics Category(s): Bio Technology (Rx, dev's, sys)

An Ex Vivo Human Multiple Myeloma Cancer Niche and Its Use As a Model for Personalized Treatment of Multiple Myeloma Background:Primary patient-derived multiple myeloma cells (MMC) are difficult to preserve . Long-term survival of osteoblasts, OSB, is the most critical factor in maintaining the ex vivo viability and proliferative capacity of MMC. The adhesion and retention of MMC to the tissue scaffold was meditated by osteoblastic N-cadherin, as one of potential... Published: 2/10/2021   |   Updated: 7/30/2018   |   Inventor(s):   Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Train-of-Four Measuring Clip A monitoring apparatus includes a clip assembly configured to be secured on a patient's digit. The clip assembly houses an accelerometer which measures acceleration in three dimensions. A microcontroller is configured to receive acceleration data from the accelerometer representative of the acceleration measured in each of the three dimensions. A processor... Published: 2/10/2021   |   Updated: 7/30/2018   |   Inventor(s): Vikki Hazelwood, Glenn Atlas, Edan Golomb, Kyle Ripley, Derek Smith, Jennifer Trinh Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

SERS-Active Fiber Probe for Kidney Transplant Acute Rejection Diagnosis SummaryA method for identifying a kidney condition of a patient includes receiving a urine sample from a patient. The patient provides the urine sample a predetermined amount of time after having been administered a dose of a sugar 5 alcohol. The method also includes determining whether the sugar alcohol is present in the urine sample. The method also... Published: 2/10/2021   |   Updated: 7/30/2018   |   Inventor(s): Henry Du, Peter Tolias, Jingmao Chi Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Gel-Tehering for Integrated Oligonnucleotide Amplification and Real-Time Detection The present invention relates to surface-patterned microgels to which molecular beacon probes are immobilized. The immobilized molecular beacon probes exhibit both low non-specific background and high specific fluorescence. Also disclosed are related arrays, related detection methods, and preparation methods.Full Patent: Gel-tethered molecular beac... Published: 2/10/2021   |   Updated: 7/30/2018   |   Inventor(s): Matthew Richardson Libera, Xiaoguang Dai, Youlong Ma Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

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